nouvelles-1 — Ingredients

Research Summary: Complementary and alternative medicine (CAM) has become increasingly popular in the United States during the last 10–15 years. The use of oral and topical supplements falls within this framework. Most oral and topical supplements are based on or include several botanical ingredients, many of which have long histories of traditional or folk medicine usage. Several of the available products derived from botanical sources are touted for their dermatologic benefits.The focus in this discussion will be on a select group of botanical compounds that have been used for dermatologic purposes or show promise for such applications. These include rosemary,...

Research Summary: Although many cosmeceutical formulations contain vitamin C and/or vitamin E, very few are actually effective in topical application. This is due to several factors. First, the concentration of these vitamins is often too low. Second, their stability is compromised once the product is opened and exposed to air and light. Third, the form of the molecule (either an ester or a mixture of isomers) may not be effectively absorbed or metabolized by the skin.However, when a stable formulation delivers a high concentration of the nonesterified, optimal isomer of the antioxidant, vitamins C and E can indeed inhibit the...

Research Summary: The purpose of this randomized, placebo-controlled, blind study was to investigate the effects of the drinkable nutraceutical ELASTEN® (QUIRIS Healthcare, Gütersloh, Germany) on skin aging and skin health. The drinkable ampoules provide a blend of 2.5 g of collagen peptides, acerola fruit extract, vitamin C, zinc, biotin, and a native vitamin E complex. This controlled interventional trial was conducted with 72 healthy women aged 35 years or older. Participants received either the food supplement (n = 36) or a placebo (n = 36) for twelve weeks. A skin assessment was performed based on objective validated methods, including corneometry...

Research Summary: It has been recognized that the vehicle in which a permeant is applied to the skin has a distinctive effect on the dermal and transdermal delivery of active ingredients. The cutaneous and percutaneous absorptions can be enhanced, for example, by an increase in thermodynamic activity, supersaturation, and penetration modifiers. Furthermore, dermal and transdermal delivery can be influenced by the interactions that may occur between the vehicle and the skin on the one hand, and interactions between the active ingredient and the skin on the other hand.Emulsions are widely used as cosmetic and pharmaceutical formulations because of their excellent...