nouvelles-1 — Ingredients

Research Summary: Enclosed is the Draft Report on the Safety Assessment of Polysilicone-11 as Used in Cosmetics (polysil122019rep). This ingredient is a crosslinked dimethylsiloxane, formed by the reaction of bis-vinyldimethicone and hydrogen dimethicone, and is reported to function as a film former in cosmetics.Following an intensive search of information in the published scientific literature, online databases, and other sources on this ingredient, there was insufficient information found to justify the preparation of a formal Scientific Literature Review (SLR). Therefore, in July 2019, CIR issued a SLR Notice to Proceed (NTP) for Polysilicone-11 to alert interested parties that a safety assessment...

Research Summary: In recent decades, there has been a rising demand for anti-aging interventions aimed at postponing or potentially reversing indicators of skin aging. The use of collagen-based nutraceutical supplements has gained popularity as they have shown promise in enhancing skin health and reducing signs of aging. The aim of this randomized, placebo-controlled, blinded study was to investigate the effects of 2.5 g COLLinstant® LMW, a novel cosmeceutical containing low molecular weight (≤ 1000 Da) collagen peptides, on skin aging and health. The trial was conducted in 80 healthy women aged 30 years and older. They received a daily oral...

Research Summary:Artocarpus heterophyllus (A. heterophyllus) is one of the plants commonly used for skin care. This study aimed to formulate a clay mask preparation with the active ingredient  A. heterophyllus 3% leaf extract and evaluate its activities in repairing facial moisture, smoothness, large pores, blemishes, and wrinkles. The process of preparing the clay masks began with the extraction of Artocarpus heterophyllus leaf ethanol extracts, ensuring standardized quality. This was followed by the preparation of clay mask bases with guaranteed quality, mixing the clay mask bases with the extracts, and testing the quality, stability, and effectiveness of the skin care product....

Research Summary: Pharmaceutical formulations in liquid form for oral administration are commonly utilized for geriatric and pediatric patients who have difficulty swallowing solid dosage forms. Rheology, texture, and stability are among the Critical Quality Attributes (CQAs) that must be addressed in the development of oral liquid dosage forms. The distribution of pharmaceutical components relies on the manipulation of rheological properties and stabilization within these forms. The utilization of thickening agents to increase the viscosity of the liquid vehicle serves to reduce particle settling. Historically, sugars such as sucrose were used for this purpose, as well as for masking the taste...