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Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Oxidative stress is the major cause of skin aging that includes wrinkles, pigmentation, and weakened wound healing ability. Application of antioxidants in skin care is well accepted as an effective approach to delay the skin aging process. Methylene blue (MB), a traditional mitochondrial-targeting antioxidant, showed a potent ROS scavenging efficacy in cultured human skin fibroblasts derived from healthy donors and from patients with progeria, a genetic premature aging disease. In comparison with other widely used general and mitochondrial-targeting antioxidants, we found that MB was more effective in stimulating skin fibroblast proliferation and delaying cellular senescence. The skin irritation test, performed...

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Lipid Nanoparticles Based Cosmetics

Lipid Nanoparticles Based Cosmetics

Abstract: The lipids mainly oils, fats, waxes and phospholipids are of substantial importance in the development and functioning of cosmetic products. The lipid nanoparticles-based cosmetic product is highly capable of protecting the skin against harmful radiations and is utilized for anti-aging therapy. Naturally derived antioxidants such as carotenoids, retinoids and tocopherols could be employed for their antioxidant properties as therapeutics and skincare active moieties in cosmetic products. Such a lipid nanoparticles-based cosmetic formulation consisting of antioxidants are very effective against irritated and inflamed skin and very promising for treating skin disorders such as atopic dermatitis and psoriasis. Therefore, the present...

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Application of Nanoparticles in Cosmetics

Application of Nanoparticles in Cosmetics

The present review aims to study a promising area of Nanoparticles used in various cosmetic products like Deodorant, Soap, Toothpaste, Shampoo, Hair conditioner, Anti-wrinkle cream, Moisturizer, Foundation, Face powder, Lipstick, Blush, Eye shadow, Nail polish, Perfume and After-shave lotion etc. In particular, NLCs have been identified as a potential next generation cosmetic delivery agent that can provide enhanced skin hydration, bioavailability, stability of the agent and controlled occlusion. Nanoparticles are synthesized by various techniques are Sol–gel Method, Vacuum Deposition Method, Ball Milling Method, Pyrolysis etc. Characterization of Nanoparticles is must necessary in order formulate Nanocosmeticeuticals. Many methods are used for...

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Effects of Air Pollution on Cellular Senescence and Skin Aging

Effects of Air Pollution on Cellular Senescence and Skin Aging

Human skin is exposed daily to various environmental factors, including air pollutants and ultraviolet (UV) light. Air pollution is recognized as a significant environmental risk to human skin, promoting aging and inflammation that lead to skin disorders, wrinkles, and pigmentation issues. Moreover, components of air pollution can synergize with UV light, amplifying skin damage. Despite this, the role of air pollution in modulating cellular senescence in skin cells and its contribution to skin aging remains poorly understood. This review summarizes the current knowledge on air pollution components, their role in cellular senescence and skin aging, and the therapeutic and cosmetic...

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